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Inhibition of SHP-1 expands the repertoire of antitumor T cells available to respond to immune checkpoint blockade.
The presence and activity of CD8(+) T cells within the tumor microenvironment is essential for the control of tumor growth. Utilizing B16-F10 melanoma tumors that express altered peptide ligands of chicken ovalbumin, OVA(257–264), we measured high- and low-affinity OVA-specific responses following a...
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| Publicado no: | Cancer Immunol Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7125038/ https://ncbi.nlm.nih.gov/pubmed/32075800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0690 |
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