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Locked Nucleic Acid: High-Affinity Targeting of Complementary RNA for RNomics
Locked nucleic acid (LNA) is a nucleic acid analog containing one or more LNA nucleotide monomers with a bicyclic furanose unit locked in an RNA-mimicking sugar conformation. This conformational restriction is translated into unprecedented hybridization affinity towards complementary single-stranded...
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| Publié dans: | RNA Towards Medicine |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7120141/ https://ncbi.nlm.nih.gov/pubmed/16594628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/3-540-27262-3_21 |
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