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Locked Nucleic Acid: High-Affinity Targeting of Complementary RNA for RNomics

Locked nucleic acid (LNA) is a nucleic acid analog containing one or more LNA nucleotide monomers with a bicyclic furanose unit locked in an RNA-mimicking sugar conformation. This conformational restriction is translated into unprecedented hybridization affinity towards complementary single-stranded...

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Detalhes bibliográficos
Publicado no:RNA Towards Medicine
Main Authors: Kauppinen, S., Vester, B., Wengel, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7120141/
https://ncbi.nlm.nih.gov/pubmed/16594628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/3-540-27262-3_21
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