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Synthesis, Affinity for Complementary RNA and DNA, and Enzymatic Stability of Triazole-Linked Locked Nucleic Acids (t-LNAs)

[Image: see text] Dinucleoside phosphoramidites containing a triazole internucleotide linkage flanked by locked nucleic acid (LNA) were synthesized and incorporated into oligonucleotides (ONs). ONs bearing both LNA and triazole at multiple sites were obtained and their biophysical properties includi...

詳細記述

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書誌詳細
出版年:ACS Omega
主要な著者: Kumar, Pawan, Truong, Lynda, Baker, Ysobel Ruth, El-Sagheer, Afaf Helmy, Brown, Tom
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2018
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028152/
https://ncbi.nlm.nih.gov/pubmed/29978149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01086
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