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Synthesis, Affinity for Complementary RNA and DNA, and Enzymatic Stability of Triazole-Linked Locked Nucleic Acids (t-LNAs)
[Image: see text] Dinucleoside phosphoramidites containing a triazole internucleotide linkage flanked by locked nucleic acid (LNA) were synthesized and incorporated into oligonucleotides (ONs). ONs bearing both LNA and triazole at multiple sites were obtained and their biophysical properties includi...
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| Wydane w: | ACS Omega |
|---|---|
| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical Society
2018
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028152/ https://ncbi.nlm.nih.gov/pubmed/29978149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01086 |
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