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Systematic Assembly and Genetic Manipulation of the Mouse Hepatitis Virus A59 Genome

We have developed a DNA assembly platform that utilizes the nonspecific, highly variable sequence signatures of type IIs restriction enzymes to assemble a full-length molecular clone of murine hepatitis coronavirus (MHV) strain A59. The approach also allows changes to be engineered into a DNA fragme...

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Bibliografiske detaljer
Udgivet i:SARS- and Other Coronaviruses
Main Authors: Donaldson, Eric F., Sims, Amy C., Baric, Ralph S.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7120124/
https://ncbi.nlm.nih.gov/pubmed/19057869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-181-9_21
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