Analysis of Murine Hepatitis Virus Strain A59 Temperature-Sensitive Mutant TS-LA6 Suggests that nsp10 Plays a Critical Role in Polyprotein Processing

Coronaviruses are the largest RNA viruses, and their genomes encode replication machinery capable of efficient replication of both positive- and negative-strand viral RNAs as well as enzymes capable of processing large viral polyproteins into putative replication intermediates and mature proteins. A...

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Главные авторы: Donaldson, Eric F., Graham, Rachel L., Sims, Amy C., Denison, Mark R., Baric, Ralph S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2007
Предметы:
Genome Replication and Regulation of Viral Gene Expression
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933295/
https://ncbi.nlm.nih.gov/pubmed/17428870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00049-07
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