Structure of the class D GPCR Ste2 dimer coupled to two G proteins

G protein-coupled receptors (GPCRs) are divided phylogenetically into six classes, A-F(1,2). Over 370 structures of vertebrate GPCRs (classes A, B, C and F) have been determined, leading to a substantial understanding of their function(3). In contrast, there are no structures of Class D GPCRs, which...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Velazhahan, Vaithish, Ma, Ning, Pándy-Szekeres, Gáspár, Kooistra, Albert J., Lee, Yang, Gloriam, David E., Vaidehi, Nagarajan, Tate, Christopher G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116888/
https://ncbi.nlm.nih.gov/pubmed/33268889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2994-1
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