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Expanding the Concept of G Protein-Coupled Receptor (GPCR) Dimer Asymmetry towards GPCR-Interacting Proteins

G protein-coupled receptors (GPCRs), major targets of drug discovery, are organized in dimeric and/or oligomeric clusters. The minimal oligomeric unit, the dimer, is composed of two protomers, which can behave differently within the dimer. Several examples of GPCR asymmetry within dimers at the leve...

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Hlavní autoři: Kamal, Maud, Maurice, Pascal, Jockers, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053957/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4020273
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