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Expanding the Concept of G Protein-Coupled Receptor (GPCR) Dimer Asymmetry towards GPCR-Interacting Proteins

G protein-coupled receptors (GPCRs), major targets of drug discovery, are organized in dimeric and/or oligomeric clusters. The minimal oligomeric unit, the dimer, is composed of two protomers, which can behave differently within the dimer. Several examples of GPCR asymmetry within dimers at the leve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kamal, Maud, Maurice, Pascal, Jockers, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053957/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4020273
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