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Centrosome Aurora A regulates RhoGEF ECT-2 localisation and ensures a single PAR-2 polarity axis in C. elegans embryos

Proper establishment of cell polarity is essential for development. In the one-cell C. elegans embryo, a centrosome-localised signal provides spatial information for polarity establishment. It is hypothesised that this signal causes local inhibition of the cortical actomyosin network, and breaks sym...

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書目詳細資料
發表在:Development
Main Authors: Kapoor, Sukriti, Kotak, Sachin
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115938/
https://ncbi.nlm.nih.gov/pubmed/31636075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.174565
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