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Pebble/ECT2 RhoGEF negatively regulates the Wingless/Wnt signaling pathway
Wingless (Wg)/Wnt signaling is essential for patterning invertebrate and vertebrate embryos, and inappropriate Wnt activity is associated with a variety of human cancers. Despite intensive study, Wnt pathway mechanisms are not fully understood. We have discovered a new mechanism for regulating the W...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848189/ https://ncbi.nlm.nih.gov/pubmed/24198276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.101303 |
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