Загрузка...

Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers()

Two-pore channels (TPCs) are Ca(2+)-permeable ion channels localised to the endo-lysosomal system where they regulate trafficking of various cargoes including viruses. As a result, TPCs are emerging as important drug targets. However, their pharmacology is ill-defined. There are no approved drugs to...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Biochim Biophys Acta Mol Cell Res
Главные авторы: Penny, Christopher J., Vassileva, Kristin, Jha, Archana, Yuan, Yu, Chee, Xavier, Yates, Elizabeth, Mazzon, Michela, Kilpatrick, Bethan S., Muallem, Shmuel, Marsh, Mark, Rahman, Taufiq, Patel, Sandip
Формат: Artigo
Язык:Inglês
Опубликовано: Published by Elsevier B.V. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114365/
https://ncbi.nlm.nih.gov/pubmed/30408544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2018.10.022
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!