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A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate()

Substrate ubiquitylation is a reversible process critical to cellular homeostasis that is often dysregulated in many human pathologies including cancer and neurodegeneration. Elucidating the mechanistic details of this pathway could unlock a large store of information useful to the design of diagnos...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Res
Main Authors: Loch, Christian M., Strickler, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113913/
https://ncbi.nlm.nih.gov/pubmed/22626734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.05.006
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