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Substrate Specificity Profiling of Histone-Modifying Enzymes by Peptide Microarray
The dynamic addition and removal of covalent posttranslational modifications (PTMs) on histone proteins serves as a major mechanism regulating chromatin-templated biological processes in eukaryotic genomes. Histone PTMs and their combinations function by directly altering the physical structure of c...
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| Veröffentlicht in: | Methods Enzymol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5322744/ https://ncbi.nlm.nih.gov/pubmed/27423856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.01.008 |
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