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Substrate Specificity Profiling of Histone-Modifying Enzymes by Peptide Microarray

The dynamic addition and removal of covalent posttranslational modifications (PTMs) on histone proteins serves as a major mechanism regulating chromatin-templated biological processes in eukaryotic genomes. Histone PTMs and their combinations function by directly altering the physical structure of c...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Cornett, E.M., Dickson, B.M., Vaughan, R.M., Krishnan, S., Trievel, R.C., Strahl, B.D., Rothbart, S.B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322744/
https://ncbi.nlm.nih.gov/pubmed/27423856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.01.008
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