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A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE

For antiviral screenings purposes, infection of cell cultures with the virus under study, should ideally result in the induction, within just a few days, of (nearly) complete CPE and allow the calculation of acceptable Z’ factors (>0.5). The human Corona virus NL63 (HCoV-NL63) causes only limited...

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Publicat a:J Virol Methods
Autors principals: Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier B.V. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112866/
https://ncbi.nlm.nih.gov/pubmed/22575574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2012.04.011
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