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A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE

For antiviral screenings purposes, infection of cell cultures with the virus under study, should ideally result in the induction, within just a few days, of (nearly) complete CPE and allow the calculation of acceptable Z’ factors (>0.5). The human Corona virus NL63 (HCoV-NL63) causes only limited...

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Pubblicato in:J Virol Methods
Autori principali: Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112866/
https://ncbi.nlm.nih.gov/pubmed/22575574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2012.04.011
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