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A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE

For antiviral screenings purposes, infection of cell cultures with the virus under study, should ideally result in the induction, within just a few days, of (nearly) complete CPE and allow the calculation of acceptable Z’ factors (>0.5). The human Corona virus NL63 (HCoV-NL63) causes only limited...

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Bibliografiske detaljer
Udgivet i:J Virol Methods
Main Authors: Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier B.V. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112866/
https://ncbi.nlm.nih.gov/pubmed/22575574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2012.04.011
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