Profiling DUBs and Ubl-specific proteases with activity-based probes

Protein (poly-)ubiquitination is a posttranslational modification that plays a key role in almost all cellular processes. It involves the installment of either single ubiquitin (Ub) moieties or one of eight different polyUb linkage types, each giving a distinct cellular outcome. Deubiquitinating enz...

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Dettagli Bibliografici
Pubblicato in:Methods Enzymol
Autori principali: Geurink, Paul P., van der Heden van Noort, Gerbrand J., Mulder, Monique P.C., Knaap, Robert C.M., Kikkert, Marjolein, Ovaa, Huib
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112362/
https://ncbi.nlm.nih.gov/pubmed/30850060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.12.037
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