Generation of the UFM1 Toolkit for Profiling UFM1‐Specific Proteases and Ligases

Ubiquitin‐fold modifier 1 (UFM1) is a reversible post‐translational modifier that is covalently attached to target proteins through an enzymatic cascade and removed by designated proteases. Abnormalities in this process, referred to as Ufmylation, have been associated with a variety of human disease...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Witting, Katharina F., van der Heden van Noort, Gerbrand J., Kofoed, Christian, Talavera Ormeño, Cami, el Atmioui, Dris, Mulder, Monique P. C., Ovaa, Huib
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220884/
https://ncbi.nlm.nih.gov/pubmed/30188611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201809232
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