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Catching a DUB in the act: novel ubiquitin-based active site directed probes
Protein ubiquitylation is an important regulator of protein function, localization and half-life. It plays a key role in most cellular processes including immune signaling. Deregulation of this process is a major causative factor for many diseases. A major advancement in the identification and chara...
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| Published in: | Curr Opin Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier Ltd.
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185813/ https://ncbi.nlm.nih.gov/pubmed/25461387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.10.005 |
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