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Catching a DUB in the act: novel ubiquitin-based active site directed probes

Protein ubiquitylation is an important regulator of protein function, localization and half-life. It plays a key role in most cellular processes including immune signaling. Deregulation of this process is a major causative factor for many diseases. A major advancement in the identification and chara...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Ekkebus, Reggy, Flierman, Dennis, Geurink, Paul P, Ovaa, Huib
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185813/
https://ncbi.nlm.nih.gov/pubmed/25461387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.10.005
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