Impact of polymorphisms in the DC-SIGNR neck domain on the interaction with pathogens

The lectins DC-SIGN and DC-SIGNR augment infection by human immunodeficiency virus (HIV), Ebolavirus (EBOV) and other pathogens. The neck domain of these proteins drives multimerization, which is believed to be required for efficient recognition of multivalent ligands. The neck domain of DC-SIGN con...

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Publicado en:Virology
Autores principales: Gramberg, Thomas, Zhu, Tuofu, Chaipan, Chawaree, Marzi, Andrea, Liu, Huanliang, Wegele, Anja, Andrus, Thomas, Hofmann, Heike, Pöhlmann, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Inc. 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111803/
https://ncbi.nlm.nih.gov/pubmed/16413044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.11.033
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