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The Signal Peptide of the Ebolavirus Glycoprotein Influences Interaction with the Cellular Lectins DC-SIGN and DC-SIGNR

The C-type lectins DC-SIGN and DC-SIGNR (collectively referred to as DC-SIGN/R) bind to the ebolavirus glycoprotein (EBOV-GP) and augment viral infectivity. DC-SIGN/R strongly enhance infection driven by the GP of EBOV subspecies. Zaire (ZEBOV) but have a much less pronounced effect on infection med...

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Detalhes bibliográficos
Main Authors: Marzi, Andrea, Akhavan, Armin, Simmons, Graham, Gramberg, Thomas, Hofmann, Heike, Bates, Paul, Lingappa, Vishwanath R., Pöhlmann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488929/
https://ncbi.nlm.nih.gov/pubmed/16775318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02545-05
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