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Impact of polymorphisms in the DC-SIGNR neck domain on the interaction with pathogens

The lectins DC-SIGN and DC-SIGNR augment infection by human immunodeficiency virus (HIV), Ebolavirus (EBOV) and other pathogens. The neck domain of these proteins drives multimerization, which is believed to be required for efficient recognition of multivalent ligands. The neck domain of DC-SIGN con...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Gramberg, Thomas, Zhu, Tuofu, Chaipan, Chawaree, Marzi, Andrea, Liu, Huanliang, Wegele, Anja, Andrus, Thomas, Hofmann, Heike, Pöhlmann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111803/
https://ncbi.nlm.nih.gov/pubmed/16413044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.11.033
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