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Substitutions of conserved amino acids in the receptor-binding domain of the spike glycoprotein affect utilization of murine CEACAM1a by the murine coronavirus MHV-A59

The host range of the murine coronavirus (MHV) is limited to susceptible mice and murine cell lines by interactions of the spike glycoprotein (S) with its receptor, mCEACAM1a. We identified five residues in S (S33, L79, T82, Y162 and K183) that are conserved in the receptor-binding domain of MHV str...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Thackray, Larissa B., Turner, Brian C., Holmes, Kathryn V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111733/
https://ncbi.nlm.nih.gov/pubmed/15749126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.01.016
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