The N-Terminal Domain of the Murine Coronavirus Spike Glycoprotein Determines the CEACAM1 Receptor Specificity of the Virus Strain

Using isogenic recombinant murine coronaviruses expressing wild-type murine hepatitis virus strain 4 (MHV-4) or MHV-A59 spike glycoproteins or chimeric MHV-4/MHV-A59 spike glycoproteins, we have demonstrated the biological functionality of the N-terminus of the spike, encompassing the receptor bindi...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Tsai, Jean C., Zelus, Bruce D., Holmes, Kathryn V., Weiss, Susan R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.841-850.2003
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