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IκB kinase ɛ (IKKɛ): A therapeutic target in inflammation and cancer
The innate immune system forms our first line of defense against invading pathogens and relies for a major part on the activation of two transcription factors, NF-κB and IRF3. Signaling pathways that activate these transcription factors are intertwined at the level of the canonical IκB kinases (IKKα...
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| Publicado no: | Biochem Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7111187/ https://ncbi.nlm.nih.gov/pubmed/23333767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.01.007 |
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