HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus

A novel coronavirus has been identified as an etiological agent of severe acute respiratory syndrome (SARS). To rapidly identify anti-SARS drugs available for clinical use, we screened a set of compounds that included antiviral drugs already in wide use. Here we report that the HIV-1 protease inhibi...

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Pubblicato in:Biochem Biophys Res Commun
Autori principali: Yamamoto, Norio, Yang, Rongge, Yoshinaka, Yoshiyuki, Amari, Shinji, Nakano, Tatsuya, Cinatl, Jindrich, Rabenau, Holger, Doerr, Hans Wilhelm, Hunsmann, Gerhard, Otaka, Akira, Tamamura, Hirokazu, Fujii, Nobutaka, Yamamoto, Naoki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111005/
https://ncbi.nlm.nih.gov/pubmed/15144898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.04.083
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