A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters

The main proteinase (M(pro)) of the severe acute respiratory syndrome (SARS) coronavirus is a principal target for the design of anticoronaviral compounds. Benzotriazole esters have been reported as potent nonpeptidic inhibitors of the enzyme, but their exact mechanism of action remains unclear. Her...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Verschueren, Koen H.G., Pumpor, Ksenia, Anemüller, Stefan, Chen, Shuai, Mesters, Jeroen R., Hilgenfeld, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110992/
https://ncbi.nlm.nih.gov/pubmed/18559270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.04.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados