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Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features
The Middle-East Respiratory Syndrome coronavirus (MERS-CoV) causes severe acute pneumonia and renal failure. The MERS-CoV papain-like protease (PL(pro)) is a potential target for the development of antiviral drugs. To facilitate these efforts, we determined the three-dimensional structure of the enz...
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| Veröffentlicht in: | Antiviral Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Authors. Published by Elsevier B.V.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7113875/ https://ncbi.nlm.nih.gov/pubmed/24992731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.06.011 |
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