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A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters
The main proteinase (M(pro)) of the severe acute respiratory syndrome (SARS) coronavirus is a principal target for the design of anticoronaviral compounds. Benzotriazole esters have been reported as potent nonpeptidic inhibitors of the enzyme, but their exact mechanism of action remains unclear. Her...
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| 發表在: | Chem Biol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier Ltd.
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7110992/ https://ncbi.nlm.nih.gov/pubmed/18559270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.04.011 |
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