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Study on Substrate Specificity at Subsites for Severe Acute Respiratory Syndrome Coronavirus 3CL Protease

Abstract Autocleavage assay and peptide‐based cleavage assay were used to study the substrate specificity of 3CL protease from the severe acute respiratory syndrome coronavirus. It was found that the recognition between the enzyme and its substrates involved many positions in the substrate, at least...

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Pubblicato in:Acta Biochim Biophys Sin (Shanghai)
Autori principali: SHAN, Yu‐Fei, XU, Gen‐Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Pty 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109883/
https://ncbi.nlm.nih.gov/pubmed/16331324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1745-7270.2005.00114.x
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