Hepatocyte‐Specific Expression of Human Carboxylesterase 1 Attenuates Diet‐Induced Steatohepatitis and Hyperlipidemia in Mice

Rodents have at least five carboxylesterase 1 (Ces1) genes, whereas there is only one CES1 gene in humans, raising the question as to whether human CES1 and mouse Ces1 genes share the same functions. In this study, we investigate the role of human CES1 in the development of steatohepatitis or dyslip...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hepatol Commun
Prif Awduron: Xu, Yanyong, Zhu, Yingdong, Bawa, Fathima Cassim, Hu, Shuwei, Pan, Xiaoli, Yin, Liya, Zhang, Yanqiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109343/
https://ncbi.nlm.nih.gov/pubmed/32258948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1487
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