Hepatocyte‐Specific Expression of Human Carboxylesterase 1 Attenuates Diet‐Induced Steatohepatitis and Hyperlipidemia in Mice

Rodents have at least five carboxylesterase 1 (Ces1) genes, whereas there is only one CES1 gene in humans, raising the question as to whether human CES1 and mouse Ces1 genes share the same functions. In this study, we investigate the role of human CES1 in the development of steatohepatitis or dyslip...

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Vydáno v:Hepatol Commun
Hlavní autoři: Xu, Yanyong, Zhu, Yingdong, Bawa, Fathima Cassim, Hu, Shuwei, Pan, Xiaoli, Yin, Liya, Zhang, Yanqiao
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109343/
https://ncbi.nlm.nih.gov/pubmed/32258948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1487
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