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Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice

Human carboxylesterase 2 (CES2) has triacylglycerol hydrolase (TGH) activities and plays an important role in lipolysis. In this study, we aim to determine the role of human CES2 in the progression or reversal of steatohepatitis in diet-induced or genetically obese mice. High-fat/high-cholesterol/hi...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Xu, Yanyong, Pan, Xiaoli, Hu, Shuwei, Zhu, Yingdong, Cassim Bawa, Fathima, Li, Yuanyuan, Yin, Liya, Zhang, Yanqiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938772/
https://ncbi.nlm.nih.gov/pubmed/33325808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00315.2020
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