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Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples
Tumour mutational burden (TMB) has emerged as a promising biomarker to predict immune checkpoint inhibitors (ICIs) response in advanced solid cancers. However, harmonisation of TMB reporting by targeted gene panels is lacking, especially in metastatic tumour samples. To address this issue, we used d...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Br J Cancer |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7109082/ https://ncbi.nlm.nih.gov/pubmed/32094484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0762-5 |
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