Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples

Tumour mutational burden (TMB) has emerged as a promising biomarker to predict immune checkpoint inhibitors (ICIs) response in advanced solid cancers. However, harmonisation of TMB reporting by targeted gene panels is lacking, especially in metastatic tumour samples. To address this issue, we used d...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Mankor, Joanne M., Paats, Marthe S., Groenendijk, Floris H., Roepman, Paul, Dinjens, Winand N. M., Dubbink, Hendrikus J., Sleijfer, Stefan, Cuppen, Edwin, Lolkema, Martijn P. J. K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109082/
https://ncbi.nlm.nih.gov/pubmed/32094484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0762-5
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker