Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer

Macrophages have been linked to tumor initiation, progression, metastasis, and treatment resistance. However, the transcriptional regulation of macrophages driving the protumor function remains elusive. Here, we demonstrate that the transcription factor c-Maf is a critical controller for immunosuppr...

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Vydáno v:J Clin Invest
Hlavní autoři: Liu, Min, Tong, Zan, Ding, Chuanlin, Luo, Fengling, Wu, Shouzhen, Wu, Caijun, Albeituni, Sabrin, He, Liqing, Hu, Xiaoling, Tieri, David, Rouchka, Eric C., Hamada, Michito, Takahashi, Satoru, Gibb, Andrew A., Kloecker, Goetz, Zhang, Huang-ge, Bousamra, Michael, Hill, Bradford G., Zhang, Xiang, Yan, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108920/
https://ncbi.nlm.nih.gov/pubmed/31945018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131335
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