Ubiquitous antigen-specific T regulatory type 1 cells variably suppress hepatic and extrahepatic autoimmunity

Peptide MHC class II–based (pMHCII-based) nanomedicines trigger the formation of multicellular regulatory networks by reprogramming autoantigen-experienced CD4(+) T cells into autoimmune disease–suppressing T regulatory type 1 (TR1) cells. We have shown that pMHCII-based nanomedicines displaying liv...

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Vydáno v:J Clin Invest
Hlavní autoři: Umeshappa, Channakeshava Sokke, Mbongue, Jacques, Singha, Santiswarup, Mohapatra, Saswat, Yamanouchi, Jun, Lee, Justin A., Nanjundappa, Roopa Hebbandi, Shao, Kun, Christen, Urs, Yang, Yang, Ellestad, Kristofor K., Santamaria, Pere
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Concise Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108901/
https://ncbi.nlm.nih.gov/pubmed/32125290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130670
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