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CD154 and IL-2 Signaling of CD4(+) T Cells Play a Critical Role in Multiple Phases of CD8(+) CTL Responses Following Adenovirus Vaccination
Adenoviral (AdV) vectors represent most commonly utilized viral vaccines in clinical studies. While the role of CD8(+) cytotoxic T lymphocyte (CTL) responses in mediating AdV-induced protection is well understood, the involvement of CD4(+) T cell-provided signals in the development of functional CD8...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465321/ https://ncbi.nlm.nih.gov/pubmed/23071696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047004 |
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