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Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines
Peptide-major histocompatibility complex class II (pMHCII)-based nanomedicines displaying tissue-specific autoantigenic epitopes can blunt specific autoimmune conditions by re-programming cognate antigen-experienced CD4+ T-cells into disease-suppressing T-regulatory type 1 (TR1) cells. Here, we show...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517389/ https://ncbi.nlm.nih.gov/pubmed/31089130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09893-5 |
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