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Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules
Assembly of soluble peptide-major histocompatibility complex class II (pMHCII) monomers into multimeric structures enables the detection of antigen-specific CD4(+) T cells in biological samples and, in some configurations, their reprogramming in vivo. Unfortunately, current MHCII-αβ chain heterodime...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820532/ https://ncbi.nlm.nih.gov/pubmed/31664029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12902-2 |
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