Lataa...

Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt

Cdk2-dependent TopBP1-treslin interaction is critical for DNA replication initiation. However, it remains unclear how this association is terminated after replication initiation is finished. Here, we demonstrate that phosphorylation of TopBP1 by Akt coincides with cyclin A activation during S and G(...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Liu, Kang, Graves, Joshua D., Lee, Yu-Ju, Lin, Fang-Tsyr, Lin, Weei-Chin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108819/
https://ncbi.nlm.nih.gov/pubmed/31964753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00599-19
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!