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The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation

Due to the rare incidence of spinal cord astrocytomas, their molecular features remain unclear. Here, we characterized the landscapes of mutations in H3 K27M, isocitrate dehydrogenase 1 (IDH1) R132H, BRAF V600E, and the TERT promoter in 83 diffuse spinal cord astrocytic tumors. Among these samples,...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Chai, Rui-Chao, Zhang, Yao-Wu, Liu, Yu-Qing, Chang, Yu-Zhou, Pang, Bo, Jiang, Tao, Jia, Wen-Qing, Wang, Yong-Zhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106747/
https://ncbi.nlm.nih.gov/pubmed/32228694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00913-w
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