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DIPG-09. HDAC INHIBITION IN THALAMIC AND SPINAL CORD H3K27M+ DIFFUSE MIDLINE GLIOMA

BACKGROUND: Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the leading cause of brain tumor-related deaths in children. There are no effective treatments and median survival remains dismal. Genomics identified a mutation in the majority of DMGs, a lysine to me...

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Publicado en:Neuro Oncol
Main Authors: Kreimer, Sara, Lin, Grant, Woo, Pamelyn, Monje-Deisseroth, Michelle
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012868/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.102
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