The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation

Due to the rare incidence of spinal cord astrocytomas, their molecular features remain unclear. Here, we characterized the landscapes of mutations in H3 K27M, isocitrate dehydrogenase 1 (IDH1) R132H, BRAF V600E, and the TERT promoter in 83 diffuse spinal cord astrocytic tumors. Among these samples,...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Chai, Rui-Chao, Zhang, Yao-Wu, Liu, Yu-Qing, Chang, Yu-Zhou, Pang, Bo, Jiang, Tao, Jia, Wen-Qing, Wang, Yong-Zhi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106747/
https://ncbi.nlm.nih.gov/pubmed/32228694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00913-w
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