The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation

Due to the rare incidence of spinal cord astrocytomas, their molecular features remain unclear. Here, we characterized the landscapes of mutations in H3 K27M, isocitrate dehydrogenase 1 (IDH1) R132H, BRAF V600E, and the TERT promoter in 83 diffuse spinal cord astrocytic tumors. Among these samples,...

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Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Chai, Rui-Chao, Zhang, Yao-Wu, Liu, Yu-Qing, Chang, Yu-Zhou, Pang, Bo, Jiang, Tao, Jia, Wen-Qing, Wang, Yong-Zhi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106747/
https://ncbi.nlm.nih.gov/pubmed/32228694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00913-w
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