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Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy
PD-1 blockade therapy has revolutionized cancer treatments. However, a substantial population of patients is unresponsive. To rescue unresponsive patients, the mechanism of unresponsiveness to PD-1 blockade therapy must be elucidated. Using a ‘bilateral tumor model’ where responsive and unresponsive...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7105382/ https://ncbi.nlm.nih.gov/pubmed/32122466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52330 |
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