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Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy

PD-1 blockade therapy has revolutionized cancer treatments. However, a substantial population of patients is unresponsive. To rescue unresponsive patients, the mechanism of unresponsiveness to PD-1 blockade therapy must be elucidated. Using a ‘bilateral tumor model’ where responsive and unresponsive...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Kumar, Alok, Chamoto, Kenji, Chowdhury, Partha S, Honjo, Tasuku
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105382/
https://ncbi.nlm.nih.gov/pubmed/32122466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52330
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