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Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy
PD-1 blockade therapy has revolutionized cancer treatments. However, a substantial population of patients is unresponsive. To rescue unresponsive patients, the mechanism of unresponsiveness to PD-1 blockade therapy must be elucidated. Using a ‘bilateral tumor model’ where responsive and unresponsive...
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| 出版年: | eLife |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7105382/ https://ncbi.nlm.nih.gov/pubmed/32122466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52330 |
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