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Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy

PD-1 blockade therapy has revolutionized cancer treatments. However, a substantial population of patients is unresponsive. To rescue unresponsive patients, the mechanism of unresponsiveness to PD-1 blockade therapy must be elucidated. Using a ‘bilateral tumor model’ where responsive and unresponsive...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Kumar, Alok, Chamoto, Kenji, Chowdhury, Partha S, Honjo, Tasuku
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105382/
https://ncbi.nlm.nih.gov/pubmed/32122466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52330
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