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Negative Regulation of Cytosolic Sensing of DNA

In mammals, cytosolic detection of nucleic acids is critical in initiating innate antiviral responses against invading pathogens (like bacteria, viruses, fungi and parasites). These programs are mediated by multiple cytosolic and endosomal sensors and adaptor molecules (c-GAS/STING axis and TLR9/MyD...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int Rev Cell Mol Biol
Main Authors: Abe, Takayuki, Shapira, Sagi D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105005/
https://ncbi.nlm.nih.gov/pubmed/30798991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ircmb.2018.09.002
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